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The Lions will play at Arrowhead Stadium without top corners Terrion Arnold and D.J. Reed, and possibly without safeties Brian Branch and Kerby Joseph due to injuries, while Chiefs quarterback Patrick Mahomes is projected to attempt between 34 and 40 passes in Week 6.
Patrick Mahomes has attempted 37 or more passes in four of his first five games, with projections for Week 6 estimating 34 to 40 attempts, primarily leaning above 35.5 due to factors including Detroit's weakened secondary and the Chiefs' underperforming ground game.
Xavier Worthy is projected to score at +145, leading Kansas City receivers in snap and route share despite an ankle issue, with an increased game volume expected against a high-scoring Lions team.
The Lions are expected to heavily utilize their rushing attack with Jahmyr Gibbs and David Montgomery, who has surpassed 55 rushing yards in three of his last four games, while facing a Chiefs defense ranked 31st in rush EPA and 28th in yards allowed per carry.
Mahomes recorded 270 yards and four touchdowns in Week 4, followed by 318 yards and a 70.7% completion rate last week, while the Lions defense, struggling against the pass due to injuries, may face an even greater challenge this week.
Williams has recorded under 44.5 receiving yards in four of five games this season, with limited targets and two catches or fewer in his last four games.
Mahomes has betting odds of +112 for 30 rushing yards, +225 for 40 yards, and +400 for 50 yards, indicating a potential boom-or-bust scenario in his rushing performance.
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